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Publications, Discovery

Scientific References – Publications

Scantox

Scantox encourages its scientists to publish and disseminate the results of their high quality research which is mostly done in close collaboration with our clients.

The following articles are hyperlinked to the original journal article or an abstract of the article:

Neurofilament-Light Chain as Biomarker of Neurodegenerative and Rare Diseases With High Translational Value

Tina Loeffler, Irene Schilcher, Stefanie Flunkert, and Birgit Hutter-Paier

Front. Neurosci., 11 June 2020

CD8 + T-cells Infiltrate Alzheimer’s Disease Brains and Regulate Neuronal- And Synapse-Related Gene Expression in APP-PS1 Transgenic Mice

Unger MS., Li E., Scharnagl L., Poupardin R., Altendorfer B., Mrowetz H., Hutter-Paier B., Weiger TM., Heneka MT., Attems J., Aigner L.

Brain Behav Immun 2020 May 29;S0889-1591(19)31573-9. doi: 10.1016/j.bbi.2020.05.070.

Transgene integration causes RARB downregulation in homozygous Tg4-42 mice.

Hinteregger B, Loeffler T, Flunkert S, Neddens J, Birner-Gruenberger R, Bayer TA, Madl T, Hutter-Paier B.

Sci Rep. 2020 Apr 14;10(1):6377. doi: 10.1038/s41598-020-63512-8.

The Leukotriene Receptor Antagonist Montelukast Reduces Alpha-Synuclein Load and Restores Memory in an Animal Model of Dementia with Lewy Bodies.

Marschallinger J., Altendorfer B., Rockenstein E., Holztrattner M., Garnweidner-Raith J. Pillichshammer N., Leister I., Hutter-Paier B., Strempfl K., Unger MS., Chishty M., Felder T., Johnson M., Attems J., Masliah E., Aigner L.

Neurotherapeutics. 2020 Feb 18. doi: 10.1007/s13311-020-00836-3.

Effector function of anti-pyroglutamate-3 Aβ antibodies affects cognitive benefit, glial activation and amyloid clearance in Alzheimer’s-like mice.

Crehan H., Liu B., Kleinschmidt M., Rahfeld JU., Le KX., Caldarone BJ., Frost JL., Hettmann T., Hutter-Paier B., O’Nuallain B., Park MA., DiCarli MF., Lues I., Schilling S., Lemere CA.

Alzheimers Res Ther. 2020 Jan 13;12(1):12. doi: 10.1186/s13195-019-0579-8.

Characterization of the visceral and neuronal phenotype of 4L/PS-NA mice modeling Gaucher disease.

Schiffer V., Santiago-Mujika E., Flunkert S., Schmidt S., Farcher M., Loeffler T., Schilcher I., Posch M., Neddens J., Sun Y., Kehr J., Hutter-Paier B.

PLoS One. 2020 Jan 13;15(1):e0227077. doi: 10.1371/journal.pone.0227077. eCollection 2020.

Plasma pharmacokinetic and metabolism of [18F]THK-5317 are dependent on sex.

Mairinger S., Filip T., Sauberer M., Flunkert S., Wanek T., Stanek J., Furtner S., Hutter-Paier B., Okamura N., Kuntner C.

Nucl Med Biol. 2020 Jan 13;84-85:28-32. doi: 10.1016/j.nucmedbio.2020.01.001.

Metabolic disease and ABHD6 alter the circulating bis(monoacylglycerol)phosphate profile in mice and humans

Grabner GF, Fawzy N, Pribasnig M, Trieb M, Taschler U, Holzer M, Schweiger M, Wolinski H, Kolb D, Horvath A, Breinbauer R, Ruelicke T, Rabl R, Lass A, Stadlbauer V, Hutter-Paier B, Stauber RE, Fickert P, Zechner R, Marsche G, Eichmann TO, Zimmermann R.

J Lipid Res. 2019 Mar 20. pii: jlr.M093351. doi: 10.1194/jlr.M093351.

Hepatic and neuronal phenotype of NPC1−/− mice

Estibaliz Santiago-Mujica, Stefanie Flunkert, Roland Rabl, Joerg Neddens, Tina Loeffler, Birgit Hutter-Paier.

Heliyon. 2019 Mar 14;5(3):e01293. doi: 10.1016/j.heliyon.2019.e01293

Correction: Further investigation of phenotypes and confounding factors of progressive ratio performance and feeding behavior in the BACHD rat model of Huntington disease.

Clemensson EKH, Clemensson LE, Fabry B, Flunkert S, Riess O, Wronski R, Nguyen HP.

PLoS One. 2019 Mar 7;14(3):e0213755. doi: 10.1371/journal.pone.0213755. eCollection 2019.